<?xml version="1.0" encoding="UTF-8"?><article xml:lang="en" article-type="research-article"><front><journal-meta><journal-id journal-id-type="pmc-domain-id">2522</journal-id><journal-id journal-id-type="pmc-domain">prsgo</journal-id><journal-title-group><journal-title>Plastic and Reconstructive Surgery Global Open</journal-title><abbrev-journal-title>Plast Reconstr Surg Glob Open</abbrev-journal-title></journal-title-group><publisher><publisher-name>Wolters Kluwer Health</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmcid">PMC13441132</article-id><article-id pub-id-type="pmcaid">13441132</article-id><article-id pub-id-type="pmcaiid">13441132</article-id><article-id pub-id-type="pmid">42559587</article-id><article-id pub-id-type="doi">10.1097/GOX.0000000000007999</article-id><title-group><article-title>Preoperative 3-dimensional Simulation in Aesthetic Surgery</article-title></title-group><contrib-group content-type="author"><contrib><name name-style="western"><surname>Atiyeh</surname><given-names initials="BS">Bishara S</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib><name name-style="western"><surname>Issa</surname><given-names initials="OB">Oussama B</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib><name name-style="western"><surname>Daoud</surname><given-names initials="FJ">Fayez J</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib><name name-style="western"><surname>Baajour</surname><given-names initials="JA">Jana A</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="author-notes" rid="_fncrsp93pmc__">✉</xref></contrib></contrib-group><aff id="aff1"><label>1</label>From the Faculty of Medicine, Division of Plastic and Reconstructive Surgery, American University of Beirut Medical Center, Beirut, Lebanon.</aff><author-notes><fn id="c1"><label>✉</label><p>Jana A. Baajour, MD, Surgery Department, Division of Plastic and Reconstructive Surgery, American University of Beirut Medical Center, Bliss Street, Hamra, Beirut, Lebanon, E-mail: <email>jb110@aub.edu.lb</email></p></fn><fn id="_fncrsp93pmc__"><label>✉</label><p>Corresponding author.</p></fn></author-notes><pub-date><day>5</day><month>8</month><year>2026</year></pub-date><volume>14</volume><issue>8</issue><fpage>e7999</fpage><page-range>e7999</page-range><pub-history><event event-type="pmc-release"><date><day>6</day><month>8</month><year>2026</year></date></event></pub-history><permissions><copyright-statement>Copyright © 2026 The Authors. Published by Wolters Kluwer Health, LLC. on behalf of The American Society of Plastic Surgeons.</copyright-statement><license><license-p>This is an open-access article distributed under the terms of the <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="https://creativecommons.org/licenses/by-nc-nd/4.0/" ext-link-type="uri">Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND)</ext-link>, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.</license-p></license></permissions><self-uri xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="gox-14-e7999.pdf" content-type="pmc-pdf"><?cloudpmc-path 4500/13441132/f08cfcd18e20/gox-14-e7999.pdf?><?cloudpmc-bucket app?><?size 1481177?></self-uri><abstract id="abstract1"><title>Abstract</title><sec id="sec1" disp-level="2"><title>Background:</title><p>Many patients cannot visualize the expected outcome of aesthetic interventions. Better than verbal descriptions and confusing diagrams, preoperative simulation of outcome displays complex ideas simply and improves surgeon–patient communication. Unfortunately, objective assessment of the factors that affect simulation accuracy is still lacking. Moreover, there is no real discussion about the ethical and legal implications of an eventual mismatch between preoperative simulation and the actual surgical outcome. This review aimed to summarize the current status of 3D simulation applications in aesthetic surgery.</p></sec><sec id="sec2" disp-level="2"><title>Methods:</title><p>A systematic literature search was conducted to identify clinical studies related to aesthetic surgery, measuring and reporting the accuracy of preoperative simulation compared with the achieved outcome.</p></sec><sec id="sec3" disp-level="2"><title>Results:</title><p>Seventeen studies (12 on breast augmentation and 5 on rhinoplasty) were identified and included for review. No studies about other aesthetic procedures were identified. Simulation accuracy varied for rhinoplasty. Although high accuracy has been reported in various 3D breast augmentation simulation software programs, dissatisfaction with the accuracy of preoperative simulation information is not negligible. Relying solely on simulation may lead to inaccuracies.</p></sec><sec id="sec4" disp-level="2"><title>Conclusions:</title><p>Undoubtedly, 3D simulation has been a significant step forward in aesthetic surgery. Originally introduced to enhance patient consultations, it is now becoming a strategic tool in planning and refining surgical interventions. The possible mismatch between simulation and outcome must be well recognized. Despite its numerous advantages, if misused, the technology can be counterproductive for both patient and surgeon. Making patients aware that simulations may not represent the final surgical outcome is essential.</p></sec></abstract><custom-meta-group><custom-meta><meta-name>status</meta-name><meta-value>released</meta-value></custom-meta><custom-meta><meta-name>display-pdf</meta-name><meta-value>yes</meta-value></custom-meta><custom-meta><meta-name>is-olf</meta-name><meta-value>no</meta-value></custom-meta><custom-meta><meta-name>is-manuscript</meta-name><meta-value>no</meta-value></custom-meta><custom-meta><meta-name>is-preprint</meta-name><meta-value>no</meta-value></custom-meta><custom-meta><meta-name>is-journal-matter</meta-name><meta-value>no</meta-value></custom-meta><custom-meta><meta-name>is-scanned</meta-name><meta-value>no</meta-value></custom-meta><custom-meta><meta-name>is-retracted</meta-name><meta-value>no</meta-value></custom-meta></custom-meta-group></article-meta><notes notes-type="article-notes"><sec id="historyarticle-meta1" sec-type="history" disp-level="2"><p>Received 2026 Feb 12; Accepted 2026 Jun 22; Collection date 2026 Aug.</p></sec></notes></front><body><boxed-text id="boxed-text1" position="float"><sec id="sec5" disp-level="1"><title>Takeaways</title><p><bold>Question:</bold> How accurate is 3D preoperative simulation in predicting outcomes of breast augmentation and rhinoplasty, and what are the implications of a mismatch?</p><p><bold>Findings:</bold> Seventeen studies (12 breast augmentation, 5 rhinoplasty) were reviewed. Accuracy is variable: breast augmentation simulation is often highly accurate, although mismatches can occur, especially in patients with complex anatomy, ptosis, or challenging implant positioning. Rhinoplasty prediction is less reliable, particularly for tip projection. Sole reliance on simulation can lead to inaccuracies.</p><p><bold>Meaning:</bold> Three-dimensional simulation aids communication and planning, but it is an approximation, not a guarantee. It requires cautious use and clear patient counseling, and cannot replace clinical judgment.</p></sec></boxed-text><sec id="sec6" disp-level="1"><title>INTRODUCTION</title><p>Central to any aesthetic procedure, patient satisfaction is influenced not only by morphological changes but also by the degree of alignment between the outcome and patient expectations, which may not be realistically attainable.<sup><xref rid="R1" ref-type="bibr">1</xref>,<xref rid="R2" ref-type="bibr">2</xref></sup> Effective patient-focused care with shared decision-making and informed consent is critical to decrease the preoperative risk of insufficient clarification of patient preferences, decisional conflicts, and patient anxiety.<sup><xref rid="R3" ref-type="bibr">3</xref>,<xref rid="R4" ref-type="bibr">4</xref></sup> Discrepancies between patient- and surgeon-perceived goals seriously harm the surgeon–patient relationship. Patient dissatisfaction may generate disputes and serious litigation.<sup><xref rid="R1" ref-type="bibr">1</xref></sup></p><p>Many patients cannot visualize the expected outcome. Verbal communication, not infrequently, fails to reach a surgical design agreed upon by both patient and surgeon.<sup><xref rid="R5" ref-type="bibr">5</xref>,<xref rid="R6" ref-type="bibr">6</xref></sup> Better than verbal descriptions and confusing diagrams, preoperative “morphed” images help bridge the communication gap and display complex ideas simply, thus significantly enhancing patient empowerment for better decision-making and potentially higher satisfaction. In emotionally charged situations, visual empowerment provides better emotional support as well.<sup><xref rid="R7" ref-type="bibr">7</xref>–<xref rid="R10" ref-type="bibr">10</xref></sup></p><p>Traditionally performed by hand or 2D computer image alterations,<sup><xref rid="R11" ref-type="bibr">11</xref>–<xref rid="R14" ref-type="bibr">14</xref></sup> 3D simulation brought a new dimension into surgical planning by improving doctor–patient communication, providing the opportunity for greater patient input during preoperative consultation, and allowing topographical measurements essential for aesthetic prediction. Its value for measuring outcomes and critical self-assessment by surgeons has been well demonstrated. The technology is also a powerful tool for teaching relationships and the resultant effects of various surgical maneuvers.<sup><xref rid="R6" ref-type="bibr">6</xref>,<xref rid="R10" ref-type="bibr">10</xref>,<xref rid="R15" ref-type="bibr">15</xref>–<xref rid="R27" ref-type="bibr">27</xref></sup></p><p>During the past 2 decades, there has been increasing awareness of 3D simulation in aesthetic surgery, driven by word-of-mouth, the internet, and social media, with patients seeking practices specifically offering this technology.<sup><xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R29" ref-type="bibr">29</xref></sup> It reportedly provides a personalized, realistic visual prediction of the outcome and allows for measurements and volume calculations in the office setting.<sup><xref rid="R1" ref-type="bibr">1</xref>,<xref rid="R3" ref-type="bibr">3</xref>,<xref rid="R8" ref-type="bibr">8</xref>,<xref rid="R20" ref-type="bibr">20</xref>,<xref rid="R30" ref-type="bibr">30</xref></sup> It also helps identify patients with unrealistic expectations and underlying body dysmorphic disorder, who are prone to persistent postoperative dissatisfaction.<sup><xref rid="R11" ref-type="bibr">11</xref>,<xref rid="R16" ref-type="bibr">16</xref>,<xref rid="R31" ref-type="bibr">31</xref></sup> It can furthermore increase consultation-to-surgery conversion.<sup><xref rid="R2" ref-type="bibr">2</xref>,<xref rid="R5" ref-type="bibr">5</xref>,<xref rid="R15" ref-type="bibr">15</xref>,<xref rid="R28" ref-type="bibr">28</xref>,<xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R33" ref-type="bibr">33</xref></sup> At present, it is used mostly for planning breast augmentation and, to a lesser extent, rhinoplasty. It is rarely used for augmentation-mastopexy, mastopexy, and reduction mammoplasty, and for soft tissue filler augmentation, gender-affirming surgery, and body contouring.<sup><xref rid="R12" ref-type="bibr">12</xref>,<xref rid="R26" ref-type="bibr">26</xref>,<xref rid="R34" ref-type="bibr">34</xref>–<xref rid="R36" ref-type="bibr">36</xref></sup></p><p>Objective assessment of the factors that affect simulation accuracy is still lacking.<sup><xref rid="R37" ref-type="bibr">37</xref>–<xref rid="R39" ref-type="bibr">39</xref></sup> There is also no real discussion about the ethical and legal implications of an eventual mismatch between simulation and the actual outcome.<sup><xref rid="R3" ref-type="bibr">3</xref></sup> The present review aimed to summarize the current status of 3D simulation in aesthetic surgery.</p></sec><sec id="sec7" disp-level="1"><title>MATERIALS AND METHODS</title><p>A comprehensive literature search of the PubMed, Embase, and Web of Science databases was conducted for English-language reports published from 2000 through January 2026 in accordance with PRISMA guidelines. The search strategy was developed using the PICO framework: population—patients undergoing aesthetic surgical procedures; intervention—3D preoperative simulation; comparison—the actual postoperative outcome; and Outcome—the accuracy of the preoperative simulation in predicting the achieved postoperative result. A nonstructured search was also conducted in addition to screening of the reference lists of retrieved studies and previously published reviews. Studies describing various 3D simulation software programs and their development, experimental studies, reviews, comments, and letters to the editor were excluded. The search algorithm is illustrated in Figure <xref rid="F1" ref-type="fig">1</xref>. Two investigators screened titles and abstracts and analyzed the full texts of selected papers for eligibility. Disagreements were resolved by consensus or discussions with the senior investigator.</p><fig id="F1" position="float"><?disp-level 2?><label>Fig. 1.</label><caption><p>PRISMA search algorithm.</p></caption><alternatives><graphic xmlns:xlink="http://www.w3.org/1999/xlink" content-type="image" xlink:href="gox-14-e7999-g001.jpg"><?cloudpmc-path blobs/4500/13441132/b28a4e00ab70/gox-14-e7999-g001.jpg?><?cloudpmc-bucket cdn?><?image-server-status LOAD_COMPLETED?><?original-height 1913?><?original-width 2400?><?scaled-height 638?><?scaled-width 800?></graphic><graphic xmlns:xlink="http://www.w3.org/1999/xlink" content-type="thumb" xlink:href="gox-14-e7999-g001.gif"><?cloudpmc-path blobs/4500/13441132/b151e3a466a3/gox-14-e7999-g001.gif?><?cloudpmc-bucket cdn?></graphic></alternatives></fig></sec><sec id="sec8" disp-level="1"><title>RESULTS</title><p>Seventeen studies (12 on breast augmentation and 5 on rhinoplasty) were identified and included for review. High accuracy of 3D simulation in predicting breast augmentation outcome has been reported.<sup><xref rid="R9" ref-type="bibr">9</xref>,<xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R40" ref-type="bibr">40</xref></sup> Roostaeian and Adams<sup><xref rid="R9" ref-type="bibr">9</xref></sup> observed 90.8% volume and 98.4% shape accuracy with Vectra (Canfield Scientific, Inc., Fairfield, NJ) simulation. Confirming that it is exceptionally accurate in predicting volume, Assaaeed et al<sup><xref rid="R40" ref-type="bibr">40</xref></sup> did not comment on breast shape. However, compared with the control, Hutchinson et al<sup><xref rid="R26" ref-type="bibr">26</xref></sup> did not demonstrate significantly improved patient satisfaction and predicted outcome scores; nevertheless, most patients would choose preoperative 3D simulation, indicating improved confidence regarding both surgeon and implant selection. In contradistinction, Vorstenbosch and Islur<sup><xref rid="R30" ref-type="bibr">30</xref></sup> reported moderate similarity between Crisalix (Virtual Aesthetics, Lausanne, Switzerland) simulations and surgical outcomes with respect to overall appearance, width, height, projection, volume, and nipple correction. Nevertheless, more similarity was observed for symmetrical than for tuberous or ptotic breasts. Although 90% of patients agreed that the outcome was similar to the simulation, and 93% were helped in choosing the implant, de Runz et al<sup><xref rid="R32" ref-type="bibr">32</xref></sup> reported that 50% still preferred different-sized implants fitted in a bra for implant selection. Evaluating the extent to which Arbrea Breast Software (Arbrea Labs, Zurich, Switzerland) simulation generates accurate outcome images, La Padula et al<sup><xref rid="R37" ref-type="bibr">37</xref></sup> reported only patient satisfaction as an indication of good similarity. However, one of their illustrations revealed a significant difference between simulation and the final outcome, indicating that patient satisfaction is not a good measure of high simulation−outcome similarity. Donfrancesco et al<sup><xref rid="R5" ref-type="bibr">5</xref></sup> documented a good 3D simulation of overall breast shape, height and width, and nipple ascent; however, cleavage can be poorly simulated due to poor accuracy in predicting implant position on the coronal axis. Uncertainties related to the patient’s chest circumference and the illusory “implant−breast complex” lateralization are also noted with apparent convexity of the central chest wall. The most accurate measurement reported by others is the sternal−nipple distance, and the least accurate is nipple−inframammary fold distance. Accuracy decreases in larger breasts.<sup><xref rid="R38" ref-type="bibr">38</xref></sup> A significant difference in mean upper and lower breast volume distribution between the simulated and actual outcomes has also been observed.<sup><xref rid="R39" ref-type="bibr">39</xref></sup> A significantly larger nipple–inframammary fold distance with 3D simulation was observed to be consistent with a tendency to choose larger implants.<sup><xref rid="R28" ref-type="bibr">28</xref></sup> Dissatisfaction with the accuracy of simulated preoperative information occurs in 25% of patients.<sup><xref rid="R41" ref-type="bibr">41</xref></sup> Relying solely on simulation may lead to inaccuracies. Therefore, clinical judgment remains superior.<sup><xref rid="R42" ref-type="bibr">42</xref></sup> Nevertheless, simulation is a valuable adjunct. It improves patients’ confidence regarding both surgeon and implant selection; however, it does not significantly impact satisfaction.<sup><xref rid="R5" ref-type="bibr">5</xref>,<xref rid="R26" ref-type="bibr">26</xref>,<xref rid="R28" ref-type="bibr">28</xref></sup> (<bold>See table, Supplemental Digital Content 1</bold>, which displays the reported similarity between 3D simulated images and actual surgical outcome of breast augmentation clinical studies and patient satisfaction, <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="https://links.lww.com/PRSGO/F137" ext-link-type="uri">https://links.lww.com/PRSGO/F137</ext-link>.) (<bold>See table, Supplemental Digital Content 2</bold>, which displays the summary of breast augmentation clinical studies retrieved for review with measured similarities between 3D simulated images and actual surgical outcome, <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="https://links.lww.com/PRSGO/F138" ext-link-type="uri">https://links.lww.com/PRSGO/F138</ext-link>.)</p><p>Simulation accuracy is variable for rhinoplasty. Although consistency with the outcome is reported,<sup><xref rid="R6" ref-type="bibr">6</xref></sup> a similarity of no more than 72% was reported by Yamamichi et al,<sup><xref rid="R1" ref-type="bibr">1</xref></sup> with significant overestimation of tip projection and increased nasal length. Significant underestimation of the columella tip angle and no significant differences in other aesthetic features were described by Adelson et al.<sup><xref rid="R16" ref-type="bibr">16</xref></sup> Choi et al<sup><xref rid="R43" ref-type="bibr">43</xref></sup> reported a correlation score of 0.672 between simulation and outcome for dorsum height, 0.842 for nasal tip projection, and 0.832 for the nasolabial angle. A surgeon panel preferred the actual outcome in 77.5% of cases compared with 22.5% of 3D simulated images.<sup><xref rid="R11" ref-type="bibr">11</xref></sup> Although simulation is reported to increase satisfaction with doctor–patient communication and not to impact satisfaction with the outcome,<sup><xref rid="R6" ref-type="bibr">6</xref></sup> higher predictive accuracy is nevertheless associated with higher patient satisfaction (Table <xref rid="T1" ref-type="table">1</xref>).<sup><xref rid="R1" ref-type="bibr">1</xref></sup>
<bold>(See table, Supplemental Digital Content 3</bold>, which displays the summary of the clinical rhinoplasty studies retrieved for review with measured similarities between 3D simulated images and actual surgical outcomes, <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="https://links.lww.com/PRSGO/F139" ext-link-type="uri">https://links.lww.com/PRSGO/F139</ext-link>.)</p><table-wrap id="T1" position="float"><?disp-level 2?><label>Table 1.</label><caption><p>Reported Similarity Between 3D Simulated Images and Actual Surgical Outcome of Rhinoplasty Clinical Studies, and Patient Satisfaction</p></caption><table frame="hsides" rules="groups"><thead><tr><th align="left" rowspan="1" colspan="1">Authors, Year, Country</th><th align="center" rowspan="1" colspan="1">Simulation Software</th><th align="center" rowspan="1" colspan="1">Outcome</th><th align="center" rowspan="1" colspan="1">Level of Evidence</th></tr></thead><tbody><tr><td align="left" rowspan="2" colspan="1">Yamamichi et al,<sup><xref rid="R1" ref-type="bibr">1</xref></sup> 2025, Japan</td><td align="left" rowspan="2" colspan="1">Crisalix</td><td align="left" rowspan="1" colspan="1">• FACE-Q scores significantly improved<break/>• Mean patient similarity score: 72.4; mean physician similarity score: 70.1<break/>• Simulated nasal length slightly greater<break/>• Simulation of tip projection significantly overestimated<break/>• Higher predictive accuracy associated with higher patient satisfaction</td><td align="center" rowspan="2" colspan="1">IV</td></tr><tr><td align="left" rowspan="1" colspan="1">• Patient satisfaction with simulation not reported</td></tr><tr><td align="left" rowspan="2" colspan="1">Li et al,<sup><xref rid="R6" ref-type="bibr">6</xref></sup> 2021, China</td><td align="left" rowspan="2" colspan="1">Inova</td><td align="left" rowspan="1" colspan="1">• Actual outcome was consistent with preoperative simulation</td><td align="center" rowspan="2" colspan="1">II</td></tr><tr><td align="left" rowspan="1" colspan="1">• No significant difference in patient satisfaction between 3D and non-3D imaging groups<break/>• Satisfaction with doctor–patient communication was significantly greater in the 3D imaging group</td></tr><tr><td align="left" rowspan="2" colspan="1">Choi et al,<sup><xref rid="R43" ref-type="bibr">43</xref></sup> 2020, South Korea</td><td align="left" rowspan="2" colspan="1">Not specified</td><td align="left" rowspan="1" colspan="1">• Nasal tip: simulation without printed guide = 0.842; simulation with printed guide = 0.955<break/>• Dorsum height: simulation without printed guide = 0.672; simulation with printed guide = 0.888<break/>• Nasolabial angle: simulation without printed guide = 0.832; simulation with printed guide = 0.930<break/>• Correlation between 3D simulation and outcome becomes 11.3% higher with printed nasal guide</td><td align="center" rowspan="2" colspan="1">III</td></tr><tr><td align="left" rowspan="1" colspan="1">• Higher patient satisfaction scores in the control group; however, there were no statistically significant differences<break/>• Satisfaction with the accuracy of simulation not measured</td></tr><tr><td align="left" rowspan="1" colspan="1">Persing et al,<sup><xref rid="R11" ref-type="bibr">11</xref></sup> 2018, United States</td><td align="left" rowspan="1" colspan="1">Vectra</td><td align="left" rowspan="1" colspan="1">• Surgeon panel preferred actual postoperative result in 77.5% of cases compared with the simulated images in 22.5% of cases<break/>• Nasal tip projection is significantly greater in the actual images compared with simulated ones</td><td align="center" rowspan="1" colspan="1">IV</td></tr><tr><td align="left" rowspan="2" colspan="1">Adelson et al,<sup><xref rid="R16" ref-type="bibr">16</xref></sup> 2008, United States</td><td align="left" rowspan="2" colspan="1">Mirror</td><td align="left" rowspan="1" colspan="1">• Simulations significantly underestimated the columella tip angle at 6 mo postoperatively<break/>• Other 4 aesthetic features were similar</td><td align="center" rowspan="2" colspan="1">IV</td></tr><tr><td align="left" rowspan="1" colspan="1">• Only 3 patients completed the questionnaire correctly<break/>• Patient satisfaction with the simulation was not reported</td></tr></tbody></table></table-wrap></sec><sec id="sec9" disp-level="1"><title>DISCUSSION</title><p>Given the wide range of opinions regarding ideal nasal aesthetics, many surgeons currently use computerized 3D simulation as a strategic tool for planning and refining the intervention. By visualizing the intended profile, simulation provides a framework for discussion of desirable and feasible alterations with patients, who thus become more reassured to proceed with the surgery.<sup><xref rid="R1" ref-type="bibr">1</xref>,<xref rid="R6" ref-type="bibr">6</xref>–<xref rid="R8" ref-type="bibr">8</xref>,<xref rid="R11" ref-type="bibr">11</xref>,<xref rid="R13" ref-type="bibr">13</xref>,<xref rid="R16" ref-type="bibr">16</xref>,<xref rid="R22" ref-type="bibr">22</xref>,<xref rid="R44" ref-type="bibr">44</xref></sup> Its value has now extended to the development of 3D-printed intraoperative surgical contour guides that directly translate the desired dorsal height and tip position, increase the efficiency of alloplastic implant carving, and facilitate the prefabrication of implants for augmentation rhinoplasty.<sup><xref rid="R6" ref-type="bibr">6</xref>,<xref rid="R20" ref-type="bibr">20</xref>,<xref rid="R43" ref-type="bibr">43</xref>,<xref rid="R45" ref-type="bibr">45</xref>–<xref rid="R47" ref-type="bibr">47</xref></sup></p><p>Although accuracy was reportedly high with Mirror (Canfield Scientific, Inc., Fairfield, NJ),<sup><xref rid="R16" ref-type="bibr">16</xref></sup> the accuracy of rhinoplasty 3D simulation remains moderate in both primary and revision surgery.<sup><xref rid="R22" ref-type="bibr">22</xref>,<xref rid="R48" ref-type="bibr">48</xref></sup> Achieving maximum benefit is hindered by surgeons’ ability to translate simulation into an achievable plan.<sup><xref rid="R11" ref-type="bibr">11</xref>,<xref rid="R17" ref-type="bibr">17</xref></sup> Outcome also depends on soft tissue factors that cannot be fully predicted,<sup><xref rid="R46" ref-type="bibr">46</xref></sup> with tip projection being a major challenge. Although it is easy to simulate with the software, the ideal tip is practically unattainable in patients with thick skin.<sup><xref rid="R48" ref-type="bibr">48</xref></sup> Compared with actual photographs, Vectra simulation is reported to be inferior to the actual aesthetic outcome, with nasal tip images appearing less smooth, projected, natural, or aesthetic.<sup><xref rid="R11" ref-type="bibr">11</xref></sup> On the other hand, tip projection is overestimated by Crisalix.<sup><xref rid="R1" ref-type="bibr">1</xref></sup> Even with great similarity, no significant difference in patient satisfaction has been reported between those who had simulation and those who did not.<sup><xref rid="R6" ref-type="bibr">6</xref>,<xref rid="R16" ref-type="bibr">16</xref></sup> The technology nevertheless remains useful for patient communication and surgical planning.<sup><xref rid="R22" ref-type="bibr">22</xref></sup></p><p>As surgeons and patients may have drastically different images of breast shape and volume,<sup><xref rid="R49" ref-type="bibr">49</xref>,<xref rid="R50" ref-type="bibr">50</xref></sup> and because outcome is dominated by the patient’s subjective visual assessment,<sup><xref rid="R4" ref-type="bibr">4</xref></sup> preoperative 3D simulation, particularly of breast augmentation,<sup><xref rid="R2" ref-type="bibr">2</xref></sup> is becoming increasingly common. It is also being increasingly used to guide patients undergoing breast reconstruction in managing their expectations.<sup><xref rid="R5" ref-type="bibr">5</xref>,<xref rid="R17" ref-type="bibr">17</xref>,<xref rid="R51" ref-type="bibr">51</xref></sup> Although there is no generalizable gold-standard protocol for volumetric measurement,<sup><xref rid="R12" ref-type="bibr">12</xref></sup> simulation is claimed to be a highly useful, reproducible tool for implant selection and for measuring anticipated volume change, similar to determining implant position on the chest wall.<sup><xref rid="R5" ref-type="bibr">5</xref>,<xref rid="R8" ref-type="bibr">8</xref>,<xref rid="R11" ref-type="bibr">11</xref>,<xref rid="R15" ref-type="bibr">15</xref>,<xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R39" ref-type="bibr">39</xref>,<xref rid="R40" ref-type="bibr">40</xref>,<xref rid="R52" ref-type="bibr">52</xref>–<xref rid="R55" ref-type="bibr">55</xref></sup></p><p>Breast characteristics and volumetric changes are a complex, dynamic process involving mechanical and biological factors.<sup><xref rid="R56" ref-type="bibr">56</xref>,<xref rid="R57" ref-type="bibr">57</xref></sup> Simulation may be suitable for small breasts with no ptosis or asymmetries.<sup><xref rid="R5" ref-type="bibr">5</xref>,<xref rid="R9" ref-type="bibr">9</xref>,<xref rid="R15" ref-type="bibr">15</xref>,<xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R40" ref-type="bibr">40</xref>,<xref rid="R52" ref-type="bibr">52</xref></sup> With Arbrea Breast Software, only volume simulation is extremely accurate.<sup><xref rid="R37" ref-type="bibr">37</xref></sup> Crisalix can accurately estimate volume in breasts with volumes less than 600 cm<sup>3</sup>,<sup><xref rid="R51" ref-type="bibr">51</xref></sup> and greater resemblance to outcomes is observed in symmetrical breasts.<sup><xref rid="R30" ref-type="bibr">30</xref></sup> Nevertheless, simulated images are often harsh and unflattering compared with actual clinical results.<sup><xref rid="R58" ref-type="bibr">58</xref></sup> Whether an accurate simulation is possible with various implant shapes or different insertion planes is also questionable.<sup><xref rid="R30" ref-type="bibr">30</xref></sup> Landmark positioning is more accurate with Vectra for thinner breast tissue and an exposed inframammary fold.<sup><xref rid="R42" ref-type="bibr">42</xref></sup> Simulated volume precision decreases with larger breasts and previous pregnancy.<sup><xref rid="R12" ref-type="bibr">12</xref>,<xref rid="R38" ref-type="bibr">38</xref></sup> The least accurate simulations occur when an implant of size 50 cc greater than the optimal volume is chosen based on measurements and inserted.<sup><xref rid="R9" ref-type="bibr">9</xref></sup> With Mirror software, it is difficult, and occasionally not possible, to perform simulation in women with large breasts, high body mass index, or high-grade ptosis.<sup><xref rid="R8" ref-type="bibr">8</xref></sup> Patients with almost any degree of ptosis are not well imaged, nor are postpartum patients with significant atrophy.<sup><xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R58" ref-type="bibr">58</xref></sup> Simulation of ptotic breasts results in overly optimistic images, whereas simulated images are much worse than actual outcomes for tuberous breasts, breasts with a wide intermammary space, or with a deflated upper pole.<sup><xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R33" ref-type="bibr">33</xref></sup></p><p>In general, simulation accuracy for breast augmentation is, at best, moderate. Very often, the simulated shape is quite different from the achieved outcome,<sup><xref rid="R15" ref-type="bibr">15</xref>,<xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R59" ref-type="bibr">59</xref></sup> with poor correlation between chosen implant volume and the visual effect generated.<sup><xref rid="R58" ref-type="bibr">58</xref></sup> Large implants may be applied with simulation programs while still producing reasonably appealing results, making patients pleased with implant sizes not suitable for them and giving them the wrong impression that they can have implants as large as they desire.<sup><xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R60" ref-type="bibr">60</xref></sup> In a comparative study, implant volumes selected with simulation underestimated the outcome, leading to erroneous implant size selection exceeding patient-specific anatomical limitations.<sup><xref rid="R58" ref-type="bibr">58</xref></sup> Reportedly, only 66% of women admit that simulation represents their actual outcome.<sup><xref rid="R31" ref-type="bibr">31</xref></sup></p><p>Uncertainties with simulation related to the patient’s chest circumference are also common, as it is not possible to evaluate the thoracic wall with surface imaging.<sup><xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R39" ref-type="bibr">39</xref>,<xref rid="R49" ref-type="bibr">49</xref>,<xref rid="R56" ref-type="bibr">56</xref>,<xref rid="R61" ref-type="bibr">61</xref></sup> Moreover, most 3D systems are set to show optimally filled breasts and tend to adjust breast shape to the chest regardless of actual implant width.<sup><xref rid="R33" ref-type="bibr">33</xref></sup> Lateral breast protrusion may also be overestimated, and medial implant borders may be less defined than in the real outcome.<sup><xref rid="R5" ref-type="bibr">5</xref></sup> Simulation limitations in showing upper pole improvements are also notable.<sup><xref rid="R60" ref-type="bibr">60</xref></sup> Moreover, as software adjusts images primarily through volume changes and does not reflect the implant areola stretching effect, nor does it illustrate changes in nipple–areola complex position, the nipple–areola complex is the area for which 3D simulation is least reliable.<sup><xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R60" ref-type="bibr">60</xref></sup> It must also be noted that certain inherent variables, such as variations in posture, affect quantifications from one image to another. Volumetric breast assessment in the supine position does not correlate with volume in the standing position.<sup><xref rid="R9" ref-type="bibr">9</xref>,<xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R61" ref-type="bibr">61</xref></sup></p><p>Current software ignores individual beauty characteristics, using predefined algorithms of linear finite elements that may not be based on databases of true, attainable outcomes.<sup><xref rid="R2" ref-type="bibr">2</xref>,<xref rid="R7" ref-type="bibr">7</xref>,<xref rid="R8" ref-type="bibr">8</xref>,<xref rid="R13" ref-type="bibr">13</xref>,<xref rid="R62" ref-type="bibr">62</xref></sup> These tools not account for breast dynamic changes due to variability in tissue mechanics and the surgeon’s approach, which interfere with actual long-term outcomes.<sup><xref rid="R39" ref-type="bibr">39</xref></sup> A new Vectra scanner with a numeric soft tissue mechanics extension model may enable realistic soft tissue deformation prediction, provided simulation is applied only to patients with minimal volume, significant inframammary crease definition, and no pregnancy history.<sup><xref rid="R52" ref-type="bibr">52</xref></sup></p><p>Incorporating real data is a new frontier to inform simulation. Artificial intelligence machine learning algorithms can guide 3D models to more intelligent and realistic designs.<sup><xref rid="R2" ref-type="bibr">2</xref>,<xref rid="R13" ref-type="bibr">13</xref>,<xref rid="R17" ref-type="bibr">17</xref>,<xref rid="R63" ref-type="bibr">63</xref>,<xref rid="R64" ref-type="bibr">64</xref></sup> Using data sets of experienced surgeons, artificial intelligence algorithms can be optimized to generate more harmonious individualized preoperative designs.<sup><xref rid="R13" ref-type="bibr">13</xref></sup> Furthermore, intraoperative augmented reality, applicable mainly to rhinoplasty, can be used to visualize differences between the planned model and the achieved outcome, allowing adjustments if necessary.<sup><xref rid="R46" ref-type="bibr">46</xref></sup></p><p>Until recently, available software was prohibitively expensive, requiring significant equipment, training, and office space. However, at present, new, simple, user-friendly programs and devices are available.<sup><xref rid="R2" ref-type="bibr">2</xref>,<xref rid="R4" ref-type="bibr">4</xref>,<xref rid="R29" ref-type="bibr">29</xref>,<xref rid="R37" ref-type="bibr">37</xref></sup> The technology has also evolved, offering major advances in quality and accuracy of image capture, postproduction processing, and simulation of potential outcomes,<sup><xref rid="R65" ref-type="bibr">65</xref></sup> even allowing preoperative online 3D simulation consultations.<sup><xref rid="R66" ref-type="bibr">66</xref></sup> Despite multiple innovative features, it must be acknowledged that young surgeons mostly lack enough experience to reproduce in practice a difficult 3D aesthetic design, whereas experienced senior surgeons lack enough time to deal with complex, time-consuming simulation tasks;<sup><xref rid="R13" ref-type="bibr">13</xref></sup> their reputation may be sufficient to build trust and confidence.</p><p>Despite numerous advantages, if misused, 3D simulation technology can become counterproductive for both patient and surgeon.<sup><xref rid="R10" ref-type="bibr">10</xref>,<xref rid="R33" ref-type="bibr">33</xref></sup> Although there is mounting evidence that visualization of potential outcomes may increase patient reassurance and confidence,<sup><xref rid="R7" ref-type="bibr">7</xref>,<xref rid="R8" ref-type="bibr">8</xref></sup> some programs may provide unrealistic simulations and can be unpredictable.<sup><xref rid="R30" ref-type="bibr">30</xref></sup> They may even lead some patients susceptible to manipulative/suggestive photographic material to expect outcomes that are not attainable.<sup><xref rid="R1" ref-type="bibr">1</xref>,<xref rid="R10" ref-type="bibr">10</xref></sup> A high level of expectation may lead to dissatisfaction and disappointment in many patients.<sup><xref rid="R8" ref-type="bibr">8</xref>,<xref rid="R10" ref-type="bibr">10</xref></sup> “Once they see it, they cannot unsee it.”<sup><xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R60" ref-type="bibr">60</xref></sup> The importance of patients having flexible expectations regarding the surgical outcome must not be overlooked, as this may be more valuable for satisfaction than a certain simulated preoperative image that narrows appreciation of the outcome to a predetermined, artificially generated reference picture.<sup><xref rid="R6" ref-type="bibr">6</xref></sup></p><p>Unfortunately, at present, none of the existing tools for visual communication can provide a consistent platform for customized breast surgery planning. Reliable quantitative interlinkage between virtual simulation and real surgery is largely lacking.<sup><xref rid="R43" ref-type="bibr">43</xref>,<xref rid="R52" ref-type="bibr">52</xref></sup> When deciding on implant volume, simulation cannot be used as a “virtual try-on fitting room.”<sup><xref rid="R33" ref-type="bibr">33</xref></sup> It is interesting to note that a significant percentage of patients demanding breast implant size change has remained unchanged despite improved simulation planning methods that theoretically should decrease the number of patients dissatisfied with their breast size.<sup><xref rid="R67" ref-type="bibr">67</xref></sup> Tissue-based methods, together with preoperative sizing with implants, remain reliable; they are more likely to contribute to high patient satisfaction.<sup><xref rid="R58" ref-type="bibr">58</xref></sup></p><p>Regardless of clear promise and initial enthusiasm, simulation technologies are still relatively new. Validated instruments to evaluate their accuracy in a variety of clinical settings are still not available.<sup><xref rid="R5" ref-type="bibr">5</xref>,<xref rid="R12" ref-type="bibr">12</xref></sup> It is becoming evident that 3D simulation is less useful in some specific clinical settings, greatly limiting its practical utility to justify the cost and effort.<sup><xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R58" ref-type="bibr">58</xref>,<xref rid="R59" ref-type="bibr">59</xref></sup> Although many large academic centers and clinics have acquired 3D imaging systems, until now, these systems do not seem to be cost-effective for peripheral centers or small-volume practices.<sup><xref rid="R61" ref-type="bibr">61</xref></sup></p><p>At present, previous patient photographs are still the primary driver for patients to undergo surgery, seconded by communication with the surgeon. Third comes 3D simulation for decision-making.<sup><xref rid="R34" ref-type="bibr">34</xref></sup> It must not be viewed as a promise of exact outcome, but rather an approximation, and should not be relied on entirely to establish a reliable surgical plan; physical measurements and the surgeon’s experience remain most reliable, and clinical judgment is still superior to simulation programs.<sup><xref rid="R33" ref-type="bibr">33</xref>,<xref rid="R40" ref-type="bibr">40</xref>,<xref rid="R42" ref-type="bibr">42</xref></sup></p><p>Nevertheless, 3D simulation has undoubtedly been a significant step forward in aesthetic surgery. However, for its successful adoption without compromising ethical standards, enhancing patient care and satisfaction by careful consideration of associated challenges is essential. Regulatory oversight is definitely required to ensure that the technology is used responsibly.<sup><xref rid="R10" ref-type="bibr">10</xref></sup> It should be acknowledged that one-third of simulated images do not accurately predict the outcome. Discussing eventual mismatches with patients is essential. Conservative imaging is also encouraged, and obtaining signed consent stating that no legal action may be taken if such a difference exists is recommended.<sup><xref rid="R5" ref-type="bibr">5</xref>,<xref rid="R19" ref-type="bibr">19</xref>,<xref rid="R20" ref-type="bibr">20</xref>,<xref rid="R30" ref-type="bibr">30</xref>,<xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R48" ref-type="bibr">48</xref></sup> With such recommendations, simulation becomes less attractive, specifically when used primarily by surgeons as a marketing tool during preoperative consultation to increase the volume of their practice.<sup><xref rid="R21" ref-type="bibr">21</xref>,<xref rid="R58" ref-type="bibr">58</xref></sup> Moreover, showing a simulation that routinely appears better than the outcome and intentionally withholding a poor simulation that may deter patients from undergoing surgery as suggested<sup><xref rid="R27" ref-type="bibr">27</xref>,<xref rid="R30" ref-type="bibr">30</xref></sup> cannot be ethically justifiable.</p><p>Concerns regarding the medicolegal implications of computer-simulated imaging in aesthetic surgery remain a topic for debate. It is important for surgeons not to simulate an outcome they cannot achieve.<sup><xref rid="R11" ref-type="bibr">11</xref>,<xref rid="R13" ref-type="bibr">13</xref></sup> Potential litigation whenever simulated visual expectation is not met can be a contentious issue.<sup><xref rid="R16" ref-type="bibr">16</xref>,<xref rid="R32" ref-type="bibr">32</xref>,<xref rid="R40" ref-type="bibr">40</xref></sup> Recently, a Brazilian judge ordered compensation for a patient because the rhinoplasty outcome did not match the 3D simulation. Although the court did not identify technical negligence, it ruled that promising a result through simulation and not delivering it constitutes a failure in the obligation. This type of ruling reinforces the jurisprudence that simulation, when presented as a “guarantee” or as something very close to reality, generates legal obligations.<sup><xref rid="R68" ref-type="bibr">68</xref></sup></p><p>This review is not without limitations due to the small number of identified studies and the limited number of patients involved. Study comparison was not feasible due to different simulation software, simulation protocols, image-capturing methods, and different time points at which similarity between simulation and actual outcome was measured, in addition to variable outcome measurement tools, carrying a nonnegligible risk of bias (Figs. <xref rid="F2" ref-type="fig">2</xref>, <xref rid="F3" ref-type="fig">3</xref>).</p><fig id="F2" position="float"><?disp-level 2?><label>Fig. 2.</label><caption><p>Risk of bias analysis of retrieved breast augmentation studies included in the review.<sup><xref rid="R69" ref-type="bibr">69</xref></sup></p></caption><alternatives><graphic xmlns:xlink="http://www.w3.org/1999/xlink" content-type="image" xlink:href="gox-14-e7999-g002.jpg"><?cloudpmc-path blobs/4500/13441132/e1c6704f53b4/gox-14-e7999-g002.jpg?><?cloudpmc-bucket cdn?><?image-server-status LOAD_COMPLETED?><?original-height 1666?><?original-width 2400?><?scaled-height 555?><?scaled-width 800?></graphic><graphic xmlns:xlink="http://www.w3.org/1999/xlink" content-type="thumb" xlink:href="gox-14-e7999-g002.gif"><?cloudpmc-path blobs/4500/13441132/76fa0c6df384/gox-14-e7999-g002.gif?><?cloudpmc-bucket cdn?></graphic></alternatives></fig><fig id="F3" position="float"><?disp-level 2?><label>Fig. 3.</label><caption><p>Risk of bias analysis of retrieved rhinoplasty studies included in the review.<sup><xref rid="R69" ref-type="bibr">69</xref></sup></p></caption><alternatives><graphic xmlns:xlink="http://www.w3.org/1999/xlink" content-type="image" xlink:href="gox-14-e7999-g003.jpg"><?cloudpmc-path blobs/4500/13441132/11edb66d263d/gox-14-e7999-g003.jpg?><?cloudpmc-bucket cdn?><?image-server-status LOAD_COMPLETED?><?original-height 914?><?original-width 2400?><?scaled-height 305?><?scaled-width 800?></graphic><graphic xmlns:xlink="http://www.w3.org/1999/xlink" content-type="thumb" xlink:href="gox-14-e7999-g003.gif"><?cloudpmc-path blobs/4500/13441132/ed26c497b8b1/gox-14-e7999-g003.gif?><?cloudpmc-bucket cdn?></graphic></alternatives></fig></sec><sec id="sec10" disp-level="1"><title>CONCLUSIONS</title><p>Originally introduced to enhance patient consultations, 3D simulation is now becoming a strategic tool in planning and refining some aesthetic surgical interventions. However, reports about similarity between simulation and actual outcome are conflicting. Mismatch with actual postoperative outcome is common, and unrealistic “morphed” images may be generated, leading some patients to expect unattainable outcomes. Litigation may potentially be a serious risk whenever simulated visual expectation is not met. Despite numerous advantages, if misused, the technology can be counterproductive for both patient and surgeon. As for informed consent, stating that simulated images do not accurately predict outcomes and that no legal action may be taken if a difference between simulation and final outcome exists is essential. Undoubtedly, there is a critical need for regulatory oversight to ensure that 3D simulation is used responsibly.</p></sec><sec id="sec11" disp-level="1"><title>DISCLOSURE</title><p>The authors have no financial interest to declare in relation to the content of this article.</p></sec><sec id="sec12" disp-level="1"><title>Supplementary Material</title><supplementary-material id="SD1" position="float"><media xmlns:xlink="http://www.w3.org/1999/xlink" id="s1" xlink:href="gox-14-e7999-s001.pdf" mimetype="application" mime-subtype="pdf"><?cloudpmc-path 4500/13441132/22214196bd18/gox-14-e7999-s001.pdf?><?cloudpmc-bucket app?><?size 141565?></media><media xmlns:xlink="http://www.w3.org/1999/xlink" id="s2" xlink:href="gox-14-e7999-s002.pdf" mimetype="application" mime-subtype="pdf"><?cloudpmc-path 4500/13441132/05ca31f41116/gox-14-e7999-s002.pdf?><?cloudpmc-bucket app?><?size 199034?></media><media xmlns:xlink="http://www.w3.org/1999/xlink" id="s3" xlink:href="gox-14-e7999-s003.pdf" mimetype="application" mime-subtype="pdf"><?cloudpmc-path 4500/13441132/5ee70d91a694/gox-14-e7999-s003.pdf?><?cloudpmc-bucket app?><?size 133483?></media></supplementary-material></sec><sec id="fn-group1" sec-type="fn-group" disp-level="1"><title>Footnotes</title><fn-group><fn id="fn1"><p>Published online 5 August 2026.</p></fn><fn id="fn2"><p>
<italic>Disclosure statements are at the end of this article, following the correspondence information.</italic>
</p></fn><fn id="fn3"><p>Related Digital Media are available in the full-text version of the article on <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="http://www.PRSGlobalOpen.com" ext-link-type="uri">www.PRSGlobalOpen.com</ext-link>.</p></fn></fn-group></sec><sec id="ref-list1" sec-type="ref-list" disp-level="1"><title>REFERENCES</title><sec id="ref-list1_sec2" disp-level="2"><ref-list><ref id="R1"><label>1.</label><mixed-citation><named-content content-type="citation-string">Yamamichi K, Nakanishi Y, Chen CY. Three-dimensional simulation accuracy and patient satisfaction with rhinoplasty.
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