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Although it is conventional wisdom that transcriptional activators stimulate Pol II recruitment and transcription initiation, recent studies indicate that Pol II binds to the promoter and initiates transcription but pauses approximately 30–60 nucleotides downstream of the transcription start site, as a result of its
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https://www.nature.com/articles/s41467-021-27944-8
Although it is conventional wisdom that transcriptional activators stimulate Pol II recruitment and transcription initiation, recent studies indicate that Pol II binds to the promoter and initiates transcription but pauses approximately 30–60 nucleotides downstream of the transcription start site, as a result of its
https://www.nature.com/articles/s41586-026-10886-w
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https://www.nature.com/articles/s41586-026-10952-3
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https://www.nature.com/articles/s43247-026-03242-3
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https://www.nature.com/articles/s41597-024-04135-w
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https://www.nature.com/articles/nature12774
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