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The results showed that, similar to HIF-1α, TRIM28 and all three subunits of DNA-PK were recruited to the HREs of two prototypical HIF target genes, ANGPTL4 (HRE is located in the 5′-flanking region, 2012 base pairs upstream of the transcription start site)24 and PDK1 (HRE is located in the first intron, 760 base
from the top result below
https://www.nature.com/articles/s41467-021-27944-8
HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia | Nature Communications
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https://www.nature.com/articles/nature12965
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https://www.nature.com/articles/s41586-026-10954-1
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https://www.nature.com/articles/s41571-026-01190-7
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https://www.nature.com/articles/s41571-026-01176-5
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https://www.nature.com/articles/s41586-026-10982-x
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https://www.nature.com/articles/s43247-026-03242-3
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https://www.nature.com/articles/s41597-024-04135-w
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https://www.nature.com/articles/d41586-026-02199-9
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https://www.nature.com/articles/nature12774
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