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Researchers generally define "specific" antibodies as those showing greater than a two-fold difference in the specificity factors for binding at the target site versus at the best nontarget site [60]
from the top result below
https://www.bioinforesearch.com/posts/histone-chip-crosslinking-methods-compared-from-formaldehyde-to-dual-fixation-for-epigenetic-research
In DNA, deoxyguanosine represents the primary target for formaldehyde crosslinking, with the Lys-dG coupling forming the predominant aminal linkage [6]