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The results showed that, similar to HIF-1α, TRIM28 and all three subunits of DNA-PK were recruited to the HREs of two prototypical HIF target genes, ANGPTL4 (HRE is located in the 5′-flanking region, 2012 base pairs upstream of the transcription start site)24 and PDK1 (HRE is located in the first intron, 760 base
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https://www.nature.com/articles/s41467-021-27944-8
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https://www.nature.com/articles/s41467-025-63315-3
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https://www.nature.com/articles/s41586-026-10949-y
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https://www.nature.com/articles/nsmb.2878
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https://www.nature.com/articles/s41586-026-10886-w
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https://www.nature.com/articles/s41594-026-01885-6
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https://www.nature.com/articles/s41594-025-01486-9
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https://www.nature.com/articles/s41586-026-10468-w
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https://www.nature.com/articles/s41467-024-55063-7
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https://www.nature.com/articles/s41467-026-77287-5
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https://www.nature.com/articles/s41589-021-00904-5
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https://www.nature.com/articles/s41534-017-0030-6
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https://www.nature.com/articles/s41467-021-27944-8/figures/6
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https://www.nature.com/articles/s41586-026-10877-x
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https://www.nature.com/articles/s41594-026-01882-9
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https://www.nature.com/articles/s41586-026-10969-8
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