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However, this glycosylation site is not formed in natural sequences due to no S/T residues at site 101
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Dataset artefacts can partially drive the measured decline in disruption

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However, previous attempts had considerable limitations: fixed tree topology, simplified evolution models, inability to handle missing data, no site rate heterogeneity and the absence of an ancestry prior34,35,36,37,38,39,40,41,42

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There was at the time no universal infrastructure available for researchers to establish long-distance collaborations, share files, post preprints, and pre-register studies